I hear you. But I just don't have faith in the community to have an intelligent discussion on medication. The risk / reward doesn't balance. Too many people here would jump at the chance to take a pill to cure their stuttering (I don't believe in cures for stuttering. I am fluent, but I will always be a stutterer. My stutter is still here, and it presents when I am mentally fatigued.) I can't find anything recent for Pagoclone, it seemed to have stalled after "questionable findings for stuttering treatment" back in 2010. Ecopipam is only at the early clinical trial stage, about where Pagoclone stalled. I understand people want to be hopeful, but you and I both realize there isn't anything on the market. I found temporary fluency via alcohol the first few times I drank. But that was just a few times. After that, the alcohol never helped with my fluency. I suspect that if your stutter is a result of anxiety, anti-anxiety meds will likely help. But such a person would do well to work on their anxiety with a therapist to achieve a more permanent solution. I am a huge advocate for speech therapy. But I'll be the first to admit that not all speech pathologist are the same. I was very fortunate to find a speech therapist that built a program that effectively helped me. It's depressing to hear about others who keep trying speech therapy, and they aren't having success. I have a lot of resentment towards the public school system. Their failure in providing effective speech therapy undermined my opinion of speech therapy for a long time. Stutterers need access to better resources. I'm not wholly opposed to medication. When used in tandem with speech (or other) therapy, I believe it can be an effective aid. But my personal belief is that no stutterer is going to find their fluency in pill form. Maybe they will for a month or two, but your not going to achieve lasting fluency via medication alone.