It takes weeks to build up in your system, but it does offer some benefits. For some more than others. Also, you need good quality Magnesium, like Mg Glycinate or Mg L-Threonate, both of which cross the blood brain barrier much more effectively than the cheap crap. B1 Thiamine / Benfotiamine is key for dopamine and GABA synthesis and energy metabolism in the brain, whereas Magnesium helps modulate neurotransmitters and calm overactivity etc… that’s why they are used together synergistically. You need to experiment with dosages and give it a few weeks to work. It doesn’t happen within days. Note, you need D3 to maximise Mg absorption too, so add that to your daily stack.