Yeah this is kinda the whole point I have been trying to say about dopamine and I always reference one paper when speaking about this. That paper is called [The Dopamine Dilemma](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898838/) and it is my favorite paper. The basic idea is that Dopamine is a lot more complicated then we think and the paper goes and does a great job at exposing the current pharmaceutical approach to conditions like ADHD, Bipolar, and Schizophrenia as not being solid enough. There is a lot of atypical responses. I was diagnosed with ADHD and then Bipolar disorder. I hate to fight with the doctor and then admited myself to a center for them to oversee me and prove to the doctor that I was not bipolar (also I learned he was taking $20k per year from the makers of latuda so I kinda figured that was why he was doing this). But I have found that my ADHD symptoms, mainly, the mood swings was helped tremendously by stimulants and so thats where i figured that many people are most likely misdiagnosed with bipolar. But to stay on subject, there was a study comparing both the use of d-amphetamine and an anti-psychotic on people who stutter. Some people responded to d-amphetamine while others responded to the anti-psychotic. The people who responded to d-amphetamine found the changes to be extremely life-changing. I feel that dopamine and stuttering are directly related but it is very hard to determine the right treatment. I have responded well to both amphetamines and anti-psychotics for stuttering so that raises questions to how we are treating stuttering if both treatment options (which are typically opposites of each other) helped me. That is also where i got the idea for my tDCS montage positioning a few months before an actual study used the same position I had guessed would help and found promising results. TDLR: I think Dopamine is a lot more complex than we think and that it won’t really be as simple as using a dopamine agonist vs antagonist. Its why I have become so focused on studying it.