Nothing too bad, maybe a little weight gain (exercise and diet would have helped, though) and a little "brain fog" but that could have been caused by something else now that I think about it. The worst thing is that when I went off it everything went right back to the way it was. So, for me it's just a band-aid, not an actual cure unless I want to keep taking it for the rest of my life... which I'm not sure is the best idea health-wise.