I think you can still contact to be a part of the Ecopipam second phase study. ​ I have heard that B1 and magnesium work for some. I will try this after I have my baby. I tried speech therapy for past 9 months but so far no improvement. ​ For me I saw significant reduction in blocks with celexa and xanax. I saw an old study where I physician took, I printed off case study and took to my physician. However I think most PWS and SLPs do not support xanax use. It was great for me for 6 years, but if I had to do over I wouldnt take everyday. I did not become dependent on medications for example I have 60 1mg pills still in my cabinet that I never took...so not tempted...but you hear stories how some do and it wrecks there life. I think there are other medications which are felt to be safer. I never looked up long term effects...I should have but did not...so I hope there are not any as I did not have side effects but do not want it find out later it for example ruined my liver.